OT: March 2020 hydroxychloroquine study

B

bitrex

Guest
No significant effect vs. control group:

<http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf>
 
bitrex wrote...
No significant effect vs. control group:
<http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf247
95de1c77c.pdf>

Too bad (expected), but there's no supply now anyway.


--
Thanks,
- Win
 
On 4/2/2020 5:46 PM, bitrex wrote:
On 4/2/2020 5:24 PM, Winfield Hill wrote:
bitrex wrote...

No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf247

95de1c77c.pdf

  Too bad (expected), but there's no supply now anyway.



Unfortunately I smell a (bio)-engineering rathole on this one. "It looks
good in the sim"

Hydroxychloroquine has been touted for decades as a quack cure-all for
all sorts of even possibly fictitious diseases like "chronic" Lyme
disease, and Morgellons disease.

Have a friend who tried it for Bechet syndrome until the new drug Humira
worked way better, a real miracle drug for that condition it seems.
500mg of HCQ make you feel like shit so maybe good as a quack cure for
that reason, feels like it's doing something
 
On Thursday, April 2, 2020 at 5:14:49 PM UTC-4, bitrex wrote:
No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf

The Chinese are probably lying so they can get it all for themselves... even though they don't need it anymore.

--

Rick C.

- Get 1,000 miles of free Supercharging
- Tesla referral code - https://ts.la/richard11209
 
On 4/2/2020 5:24 PM, Winfield Hill wrote:
bitrex wrote...

No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf247
95de1c77c.pdf

Too bad (expected), but there's no supply now anyway.

Unfortunately I smell a (bio)-engineering rathole on this one. "It looks
good in the sim"

Hydroxychloroquine has been touted for decades as a quack cure-all for
all sorts of even possibly fictitious diseases like "chronic" Lyme
disease, and Morgellons disease.

It has an anti-inflammatory/immuno-suppressant effect so might save some
lives of severely ill patients if they're being taken down mostly by
their own immune system as looks like sometimes happens with this,
"cytokine storm" I see it's called. and other drugs with that effect
would probably help, too. but the jury is still out on whether it does a
thing to prevent the illness from evolving to that state.
 
On Thu, 2 Apr 2020 17:14:45 -0400, bitrex <user@example.net> wrote:

No significant effect vs. control group:
http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf

Mar 20, 2020
"Hydroxychloroquine and azithromycin as a treatment of COVID-19:
results of an open-label non-randomized clinical trial"
<https://www.sciencedirect.com/science/article/pii/S0924857920300996>
Conclusion
Despite its small sample size our survey shows that
hydroxychloroquine treatment is significantly associated
with viral load reduction/disappearance in COVID-19
patients and its effect is reinforced by azithromycin.


Mar 31, 2020
"Comparing HydroxyChloroquine Trials"
<https://blogs.sciencemag.org/pipeline/archives/2020/03/31/comparing-chloroquine-trials>
So you can see that these two came out rather
differently, with the Zhejiang study showing no
detectable difference on treatment and the Wuhan
one showing what looks like a real effect, especially
on radiological progression of pneumonia ...

Mar 31, 2020
"Efficacy of hydroxychloroquine in patients with COVID-19: results of
a randomized clinical trial"
<https://www.medrxiv.org/content/10.1101/2020.03.22.20040758v2>
Among patients with COVID-19, the use of HCQ could
significantly shorten TTCR and promote the
absorption of pneumonia.

Mar 31, 2020
"What's Working for COVID-19 Patients"
<https://journals.lww.com/em-news/blog/BreakingNews/pages/post.aspx>
Lots of detail what's being done to treat COVID-19 in Queens, NY.

--
Jeff Liebermann jeffl@cruzio.com
150 Felker St #D http://www.LearnByDestroying.com
Santa Cruz CA 95060 http://802.11junk.com
Skype: JeffLiebermann AE6KS 831-336-2558
 
On 4/2/2020 5:52 PM, Rick C wrote:
On Thursday, April 2, 2020 at 5:14:49 PM UTC-4, bitrex wrote:
No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf

The Chinese are probably lying so they can get it all for themselves... even though they don't need it anymore.

the FDA has pretty much nothing to lose by just turning the meds loose.
The Trumpers are demanding it, it'll be months or years before anything
conclusive is known. Some Americans live, some Americans die (and
probably at a higher rate than most other places) and you can always
claim "great success!"

<https://pics.me.me/thumb_very-nice-great-success-great-succes-borat-very-nice-50474139.png>

afterwards and that more would have if you hadn't and nobody can prove
you wrong, or at least not anytime soon or in a paper anyone will read.

Only people very annoyed will be lupus and arthritis patients who used
the drugs before and can't get 'em and the people who die of
side-effects and they don't have a lobbying firm with which to complain.
 
On Thursday, April 2, 2020 at 6:21:23 PM UTC-4, bitrex wrote:
On 4/2/2020 5:52 PM, Rick C wrote:
On Thursday, April 2, 2020 at 5:14:49 PM UTC-4, bitrex wrote:
No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf

The Chinese are probably lying so they can get it all for themselves... even though they don't need it anymore.


the FDA has pretty much nothing to lose by just turning the meds loose.
The Trumpers are demanding it, it'll be months or years before anything
conclusive is known. Some Americans live, some Americans die (and
probably at a higher rate than most other places) and you can always
claim "great success!"

https://pics.me.me/thumb_very-nice-great-success-great-succes-borat-very-nice-50474139.png

afterwards and that more would have if you hadn't and nobody can prove
you wrong, or at least not anytime soon or in a paper anyone will read.

Only people very annoyed will be lupus and arthritis patients who used
the drugs before and can't get 'em and the people who die of
side-effects and they don't have a lobbying firm with which to complain.

If you stopped reading only liberal news sites, you would know that several large pharmaceutical companies are making large production runs of Hydroxychloroquine to ensure a steady supply. For instance, Novatris is supplying up to 130 million free doses. <https://www.novartis.com/news/media-releases/novartis-commits-donate-130-million-doses-hydroxychloroquine-support-global-covid-19-pandemic-response>
 
On 4/2/2020 7:04 PM, Michael Terrell wrote:
On Thursday, April 2, 2020 at 6:21:23 PM UTC-4, bitrex wrote:
On 4/2/2020 5:52 PM, Rick C wrote:
On Thursday, April 2, 2020 at 5:14:49 PM UTC-4, bitrex wrote:
No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf

The Chinese are probably lying so they can get it all for themselves... even though they don't need it anymore.


the FDA has pretty much nothing to lose by just turning the meds loose.
The Trumpers are demanding it, it'll be months or years before anything
conclusive is known. Some Americans live, some Americans die (and
probably at a higher rate than most other places) and you can always
claim "great success!"

https://pics.me.me/thumb_very-nice-great-success-great-succes-borat-very-nice-50474139.png

afterwards and that more would have if you hadn't and nobody can prove
you wrong, or at least not anytime soon or in a paper anyone will read.

Only people very annoyed will be lupus and arthritis patients who used
the drugs before and can't get 'em and the people who die of
side-effects and they don't have a lobbying firm with which to complain.

If you stopped reading only liberal news sites, you would know that several large pharmaceutical companies are making large production runs of Hydroxychloroquine to ensure a steady supply. For instance, Novatris is supplying up to 130 million free doses. <https://www.novartis.com/news/media-releases/novartis-commits-donate-130-million-doses-hydroxychloroquine-support-global-covid-19-pandemic-response

Entirely tangential to the question of whether the drug actually does
anything. It's pretty cheap to produce. Don't expect anyone particularly
wants to be the company to tell the Trump FDA "nah we'll wait on more
clinical evidence"

It works great they're heroes, it doesn't well they'll get
taxpayer-reimbursed either way. And whether it works great or not it
will be claimed it worked great by the faithful.
 
On Thursday, April 2, 2020 at 9:27:03 PM UTC-4, bitrex wrote:
On 4/2/2020 8:48 PM, Ricky C wrote:
On Thursday, April 2, 2020 at 7:04:45 PM UTC-4, Michael Terrell wrote:
On Thursday, April 2, 2020 at 6:21:23 PM UTC-4, bitrex wrote:
On 4/2/2020 5:52 PM, Rick C wrote:
On Thursday, April 2, 2020 at 5:14:49 PM UTC-4, bitrex wrote:
No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf

The Chinese are probably lying so they can get it all for themselves.... even though they don't need it anymore.


the FDA has pretty much nothing to lose by just turning the meds loose.
The Trumpers are demanding it, it'll be months or years before anything
conclusive is known. Some Americans live, some Americans die (and
probably at a higher rate than most other places) and you can always
claim "great success!"

https://pics.me.me/thumb_very-nice-great-success-great-succes-borat-very-nice-50474139.png

afterwards and that more would have if you hadn't and nobody can prove
you wrong, or at least not anytime soon or in a paper anyone will read.

Only people very annoyed will be lupus and arthritis patients who used
the drugs before and can't get 'em and the people who die of
side-effects and they don't have a lobbying firm with which to complain.

If you stopped reading only liberal news sites, you would know that several large pharmaceutical companies are making large production runs of Hydroxychloroquine to ensure a steady supply. For instance, Novatris is supplying up to 130 million free doses. <https://www.novartis.com/news/media-releases/novartis-commits-donate-130-million-doses-hydroxychloroquine-support-global-covid-19-pandemic-response

Yeah, they are ramping up ventilator production too. But when will there be results?

Why do people talk in terms of "up to"??? So one would be included in "up to 130 million".


I hope as much as anyone they got something in the catalog that's
effective and can be deployed soon, whether it's this or something else
I don't particularly care; I have an 82 y/o mother and a per-existing
condition myself and would not be optimistic about our own chances. If
Donald Trump himself discovers M&Ms cures it tomorrow I will sing his
praises (at least on that issue) to the heavens.

But I'm skeptical. Combos of antibiotics and HCQ have been touted as
miracle cures for lots of things over the years, mostly by quacks. "do
the research." The particular treatment in question has a dubious
provenance.

Trump has known all along what cures it, taco bowls! Isn't that what he ran his campaign on?

--

Rick C.

-- Get 1,000 miles of free Supercharging
-- Tesla referral code - https://ts.la/richard11209
 
On Thursday, April 2, 2020 at 7:04:45 PM UTC-4, Michael Terrell wrote:
On Thursday, April 2, 2020 at 6:21:23 PM UTC-4, bitrex wrote:
On 4/2/2020 5:52 PM, Rick C wrote:
On Thursday, April 2, 2020 at 5:14:49 PM UTC-4, bitrex wrote:
No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf

The Chinese are probably lying so they can get it all for themselves.... even though they don't need it anymore.


the FDA has pretty much nothing to lose by just turning the meds loose.
The Trumpers are demanding it, it'll be months or years before anything
conclusive is known. Some Americans live, some Americans die (and
probably at a higher rate than most other places) and you can always
claim "great success!"

https://pics.me.me/thumb_very-nice-great-success-great-succes-borat-very-nice-50474139.png

afterwards and that more would have if you hadn't and nobody can prove
you wrong, or at least not anytime soon or in a paper anyone will read.

Only people very annoyed will be lupus and arthritis patients who used
the drugs before and can't get 'em and the people who die of
side-effects and they don't have a lobbying firm with which to complain..

If you stopped reading only liberal news sites, you would know that several large pharmaceutical companies are making large production runs of Hydroxychloroquine to ensure a steady supply. For instance, Novatris is supplying up to 130 million free doses. <https://www.novartis.com/news/media-releases/novartis-commits-donate-130-million-doses-hydroxychloroquine-support-global-covid-19-pandemic-response

Yeah, they are ramping up ventilator production too. But when will there be results?

Why do people talk in terms of "up to"??? So one would be included in "up to 130 million".

--

Rick C.

+ Get 1,000 miles of free Supercharging
+ Tesla referral code - https://ts.la/richard11209
 
On 4/2/2020 8:48 PM, Ricky C wrote:
On Thursday, April 2, 2020 at 7:04:45 PM UTC-4, Michael Terrell wrote:
On Thursday, April 2, 2020 at 6:21:23 PM UTC-4, bitrex wrote:
On 4/2/2020 5:52 PM, Rick C wrote:
On Thursday, April 2, 2020 at 5:14:49 PM UTC-4, bitrex wrote:
No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf

The Chinese are probably lying so they can get it all for themselves... even though they don't need it anymore.


the FDA has pretty much nothing to lose by just turning the meds loose.
The Trumpers are demanding it, it'll be months or years before anything
conclusive is known. Some Americans live, some Americans die (and
probably at a higher rate than most other places) and you can always
claim "great success!"

https://pics.me.me/thumb_very-nice-great-success-great-succes-borat-very-nice-50474139.png

afterwards and that more would have if you hadn't and nobody can prove
you wrong, or at least not anytime soon or in a paper anyone will read.

Only people very annoyed will be lupus and arthritis patients who used
the drugs before and can't get 'em and the people who die of
side-effects and they don't have a lobbying firm with which to complain.

If you stopped reading only liberal news sites, you would know that several large pharmaceutical companies are making large production runs of Hydroxychloroquine to ensure a steady supply. For instance, Novatris is supplying up to 130 million free doses. <https://www.novartis.com/news/media-releases/novartis-commits-donate-130-million-doses-hydroxychloroquine-support-global-covid-19-pandemic-response

Yeah, they are ramping up ventilator production too. But when will there be results?

Why do people talk in terms of "up to"??? So one would be included in "up to 130 million".

I hope as much as anyone they got something in the catalog that's
effective and can be deployed soon, whether it's this or something else
I don't particularly care; I have an 82 y/o mother and a per-existing
condition myself and would not be optimistic about our own chances. If
Donald Trump himself discovers M&Ms cures it tomorrow I will sing his
praises (at least on that issue) to the heavens.

But I'm skeptical. Combos of antibiotics and HCQ have been touted as
miracle cures for lots of things over the years, mostly by quacks. "do
the research." The particular treatment in question has a dubious
provenance.
 
On 4/2/2020 9:43 PM, Ricky C wrote:
On Thursday, April 2, 2020 at 9:27:03 PM UTC-4, bitrex wrote:
On 4/2/2020 8:48 PM, Ricky C wrote:
On Thursday, April 2, 2020 at 7:04:45 PM UTC-4, Michael Terrell wrote:
On Thursday, April 2, 2020 at 6:21:23 PM UTC-4, bitrex wrote:
On 4/2/2020 5:52 PM, Rick C wrote:
On Thursday, April 2, 2020 at 5:14:49 PM UTC-4, bitrex wrote:
No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf

The Chinese are probably lying so they can get it all for themselves... even though they don't need it anymore.


the FDA has pretty much nothing to lose by just turning the meds loose.
The Trumpers are demanding it, it'll be months or years before anything
conclusive is known. Some Americans live, some Americans die (and
probably at a higher rate than most other places) and you can always
claim "great success!"

https://pics.me.me/thumb_very-nice-great-success-great-succes-borat-very-nice-50474139.png

afterwards and that more would have if you hadn't and nobody can prove
you wrong, or at least not anytime soon or in a paper anyone will read.

Only people very annoyed will be lupus and arthritis patients who used
the drugs before and can't get 'em and the people who die of
side-effects and they don't have a lobbying firm with which to complain.

If you stopped reading only liberal news sites, you would know that several large pharmaceutical companies are making large production runs of Hydroxychloroquine to ensure a steady supply. For instance, Novatris is supplying up to 130 million free doses. <https://www.novartis.com/news/media-releases/novartis-commits-donate-130-million-doses-hydroxychloroquine-support-global-covid-19-pandemic-response

Yeah, they are ramping up ventilator production too. But when will there be results?

Why do people talk in terms of "up to"??? So one would be included in "up to 130 million".


I hope as much as anyone they got something in the catalog that's
effective and can be deployed soon, whether it's this or something else
I don't particularly care; I have an 82 y/o mother and a per-existing
condition myself and would not be optimistic about our own chances. If
Donald Trump himself discovers M&Ms cures it tomorrow I will sing his
praises (at least on that issue) to the heavens.

But I'm skeptical. Combos of antibiotics and HCQ have been touted as
miracle cures for lots of things over the years, mostly by quacks. "do
the research." The particular treatment in question has a dubious
provenance.

Trump has known all along what cures it, taco bowls! Isn't that what he ran his campaign on?

They do fix hunger I'll give him that. He runs some decent
man-of-the-people game (though poor whites, blacks and Hispanics alike
didn't tend to vote for him, seems to appeal most to upper-middle-class
suburban "renegades" around here, lol), I'm not much of a food snob.

I was 35 probably before I ate at a Ruth's Chris or Del Frisco's and was
surprised at just how kinda OK it was for the price, the Brazilian
steakhouse Fogo de Chao down the street is better for less money. Wait,
I guess that makes me a food snob, now. Ungh.
 
On Thu, 2 Apr 2020 17:14:45 -0400, bitrex <user@example.net> wrote:

No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf


Not sure how well that study was done and remember that it is from
China so I'm not sure I would believe just one study from China
anyway.

hydroxychloroquine is an ionophore which just makes a way for zinc to
get into the cells and do its thing to stop the virus from
replicating.
Maybe the people in that study had too low of zinc levels ?
 
On 4/3/2020 1:17 AM, boB wrote:
On Thu, 2 Apr 2020 17:14:45 -0400, bitrex <user@example.net> wrote:

No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf



Not sure how well that study was done and remember that it is from
China so I'm not sure I would believe just one study from China
anyway.

hydroxychloroquine is an ionophore which just makes a way for zinc to
get into the cells and do its thing to stop the virus from
replicating.
Maybe the people in that study had too low of zinc levels ?

Here is another interesting paper:

<https://www.cnn.com/2020/03/19/us/fastest-supercomputer-coronavirus-scn-trnd/index.html>

"The supercomputer ran simulations of over 8,000 compounds that could
bind to the spike protein of the virus, which could limit its ability to
spread to host cells. Summit identified 77 of them and ranked them based
on how likely they were to bind to the spike."

<https://chemrxiv.org/articles/Repurposing_Therapeutics_for_the_Wuhan_Coronavirus_nCov-2019_Supercomputer-Based_Docking_to_the_Viral_S_Protein_and_Human_ACE2_Interface/11871402/3>

One of the top four is eriodictyol. Yerba santa extract, you can get it
in a nasal spray. I tried some of the spray, who knows about c-19 but it
does seem good for my springtime allergies, seems to really clear up the
sinuses.
 
On Thursday, April 2, 2020 at 7:04:45 PM UTC-4, Michael Terrell wrote:
On Thursday, April 2, 2020 at 6:21:23 PM UTC-4, bitrex wrote:
On 4/2/2020 5:52 PM, Rick C wrote:
On Thursday, April 2, 2020 at 5:14:49 PM UTC-4, bitrex wrote:
No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf

The Chinese are probably lying so they can get it all for themselves.... even though they don't need it anymore.


the FDA has pretty much nothing to lose by just turning the meds loose.
The Trumpers are demanding it, it'll be months or years before anything
conclusive is known. Some Americans live, some Americans die (and
probably at a higher rate than most other places) and you can always
claim "great success!"

https://pics.me.me/thumb_very-nice-great-success-great-succes-borat-very-nice-50474139.png

afterwards and that more would have if you hadn't and nobody can prove
you wrong, or at least not anytime soon or in a paper anyone will read.

Only people very annoyed will be lupus and arthritis patients who used
the drugs before and can't get 'em and the people who die of
side-effects and they don't have a lobbying firm with which to complain..

If you stopped reading only liberal news sites, you would know that several large pharmaceutical companies are making large production runs of Hydroxychloroquine to ensure a steady supply. For instance, Novatris is supplying up to 130 million free doses. <https://www.novartis.com/news/media-releases/novartis-commits-donate-130-million-doses-hydroxychloroquine-support-global-covid-19-pandemic-response

From what I understand the studies are being done in the US now and we'll
know something later this month.
From here,
http://podcasts.joerogan.net/podcasts/dr-peter-hotez

George H.
 
boB <boB@K7IQ.com> wrote in
news:0m2g8f9bh0ngobn7s1g7ubm9dn5k9h70pg@4ax.com:

On Fri, 3 Apr 2020 03:32:38 -0400, bitrex <user@example.net
wrote:

On 4/3/2020 1:17 AM, boB wrote:
On Thu, 2 Apr 2020 17:14:45 -0400, bitrex <user@example.net
wrote:

No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f86
25d4dc74e42bbcf24795de1c77c.pdf



Not sure how well that study was done and remember that it is
from China so I'm not sure I would believe just one study from
China anyway.

hydroxychloroquine is an ionophore which just makes a way for
zinc to get into the cells and do its thing to stop the virus
from replicating.
Maybe the people in that study had too low of zinc levels ?


Here is another interesting paper:

https://www.cnn.com/2020/03/19/us/fastest-supercomputer-coronaviru
s-scn-trnd/index.html

"The supercomputer ran simulations of over 8,000 compounds that
could bind to the spike protein of the virus, which could limit
its ability to spread to host cells. Summit identified 77 of them
and ranked them based on how likely they were to bind to the
spike."

https://chemrxiv.org/articles/Repurposing_Therapeutics_for_the_Wuh
an_Coronavirus_nCov-2019_Supercomputer-Based_Docking_to_the_Viral_S
_Protein_and_Human_ACE2_Interface/11871402/3

One of the top four is eriodictyol. Yerba santa extract, you can
get it in a nasal spray. I tried some of the spray, who knows
about c-19 but it does seem good for my springtime allergies,
seems to really clear up the sinuses.


Thanks for the links. All good stuff that they need to try !

It may very well be that the hydroxychloroquine will only work for
Sars-Covid-2 in vitro. We will see.

I have a feeling that something will work within a few months but
not a vaccine because of all the testing needed that makes it take
a long time. Anti-virals can work pretty well though for a lot of
people.

Good luck to us all !

Get yer Zinc up!
 
On Fri, 3 Apr 2020 03:32:38 -0400, bitrex <user@example.net> wrote:

On 4/3/2020 1:17 AM, boB wrote:
On Thu, 2 Apr 2020 17:14:45 -0400, bitrex <user@example.net> wrote:

No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f8625d4dc74e42bbcf24795de1c77c.pdf



Not sure how well that study was done and remember that it is from
China so I'm not sure I would believe just one study from China
anyway.

hydroxychloroquine is an ionophore which just makes a way for zinc to
get into the cells and do its thing to stop the virus from
replicating.
Maybe the people in that study had too low of zinc levels ?


Here is another interesting paper:

https://www.cnn.com/2020/03/19/us/fastest-supercomputer-coronavirus-scn-trnd/index.html

"The supercomputer ran simulations of over 8,000 compounds that could
bind to the spike protein of the virus, which could limit its ability to
spread to host cells. Summit identified 77 of them and ranked them based
on how likely they were to bind to the spike."

https://chemrxiv.org/articles/Repurposing_Therapeutics_for_the_Wuhan_Coronavirus_nCov-2019_Supercomputer-Based_Docking_to_the_Viral_S_Protein_and_Human_ACE2_Interface/11871402/3

One of the top four is eriodictyol. Yerba santa extract, you can get it
in a nasal spray. I tried some of the spray, who knows about c-19 but it
does seem good for my springtime allergies, seems to really clear up the
sinuses.

Thanks for the links. All good stuff that they need to try !

It may very well be that the hydroxychloroquine will only work for
Sars-Covid-2 in vitro. We will see.

I have a feeling that something will work within a few months but not
a vaccine because of all the testing needed that makes it take a long
time. Anti-virals can work pretty well though for a lot of people.

Good luck to us all !
 
On Sat, 4 Apr 2020 04:22:59 +0000 (UTC),
DecadentLinuxUserNumeroUno@decadence.org wrote:

boB <boB@K7IQ.com> wrote in
news:0m2g8f9bh0ngobn7s1g7ubm9dn5k9h70pg@4ax.com:

On Fri, 3 Apr 2020 03:32:38 -0400, bitrex <user@example.net
wrote:

On 4/3/2020 1:17 AM, boB wrote:
On Thu, 2 Apr 2020 17:14:45 -0400, bitrex <user@example.net
wrote:

No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f86
25d4dc74e42bbcf24795de1c77c.pdf



Not sure how well that study was done and remember that it is
from China so I'm not sure I would believe just one study from
China anyway.

hydroxychloroquine is an ionophore which just makes a way for
zinc to get into the cells and do its thing to stop the virus
from replicating.
Maybe the people in that study had too low of zinc levels ?


Here is another interesting paper:

https://www.cnn.com/2020/03/19/us/fastest-supercomputer-coronaviru
s-scn-trnd/index.html

"The supercomputer ran simulations of over 8,000 compounds that
could bind to the spike protein of the virus, which could limit
its ability to spread to host cells. Summit identified 77 of them
and ranked them based on how likely they were to bind to the
spike."

https://chemrxiv.org/articles/Repurposing_Therapeutics_for_the_Wuh
an_Coronavirus_nCov-2019_Supercomputer-Based_Docking_to_the_Viral_S
_Protein_and_Human_ACE2_Interface/11871402/3

One of the top four is eriodictyol. Yerba santa extract, you can
get it in a nasal spray. I tried some of the spray, who knows
about c-19 but it does seem good for my springtime allergies,
seems to really clear up the sinuses.


Thanks for the links. All good stuff that they need to try !

It may very well be that the hydroxychloroquine will only work for
Sars-Covid-2 in vitro. We will see.

I have a feeling that something will work within a few months but
not a vaccine because of all the testing needed that makes it take
a long time. Anti-virals can work pretty well though for a lot of
people.

Good luck to us all !

Get yer Zinc up!

So, Some good news

https://thetexan.news/front-line-er-physician-in-dallas-sees-coronavirus-treatment-success/



And also...

Hydroxychloroquine and azithromycin as a treatment of COVID-19:
results of an open-label non-randomized clinical trial

https://www.sciencedirect.com/science/article/pii/S0924857920300996?via%3Dihub


Conclusion
Despite its small sample size our survey shows that hydroxychloroquine
treatment is significantly associated with viral load
reduction/disappearance in COVID-19 patients and its effect is
reinforced by azithromycin.
 
On Saturday, April 4, 2020 at 2:21:02 PM UTC-7, boB wrote:
On Sat, 4 Apr 2020 04:22:59 +0000 (UTC),
DecadentLinuxUserNumeroUno@decadence.org wrote:

boB <boB@K7IQ.com> wrote in
news:0m2g8f9bh0ngobn7s1g7ubm9dn5k9h70pg@4ax.com:

On Fri, 3 Apr 2020 03:32:38 -0400, bitrex <user@example.net
wrote:

On 4/3/2020 1:17 AM, boB wrote:
On Thu, 2 Apr 2020 17:14:45 -0400, bitrex <user@example.net
wrote:

No significant effect vs. control group:

http://subject.med.wanfangdata.com.cn/UpLoad/Files/202003/43f86
25d4dc74e42bbcf24795de1c77c.pdf



Not sure how well that study was done and remember that it is
from China so I'm not sure I would believe just one study from
China anyway.

hydroxychloroquine is an ionophore which just makes a way for
zinc to get into the cells and do its thing to stop the virus
from replicating.
Maybe the people in that study had too low of zinc levels ?


Here is another interesting paper:

https://www.cnn.com/2020/03/19/us/fastest-supercomputer-coronaviru
s-scn-trnd/index.html

"The supercomputer ran simulations of over 8,000 compounds that
could bind to the spike protein of the virus, which could limit
its ability to spread to host cells. Summit identified 77 of them
and ranked them based on how likely they were to bind to the
spike."

https://chemrxiv.org/articles/Repurposing_Therapeutics_for_the_Wuh
an_Coronavirus_nCov-2019_Supercomputer-Based_Docking_to_the_Viral_S
_Protein_and_Human_ACE2_Interface/11871402/3

One of the top four is eriodictyol. Yerba santa extract, you can
get it in a nasal spray. I tried some of the spray, who knows
about c-19 but it does seem good for my springtime allergies,
seems to really clear up the sinuses.


Thanks for the links. All good stuff that they need to try !

It may very well be that the hydroxychloroquine will only work for
Sars-Covid-2 in vitro. We will see.

I have a feeling that something will work within a few months but
not a vaccine because of all the testing needed that makes it take
a long time. Anti-virals can work pretty well though for a lot of
people.

Good luck to us all !

Get yer Zinc up!


So, Some good news

https://thetexan.news/front-line-er-physician-in-dallas-sees-coronavirus-treatment-success/



And also...

Hydroxychloroquine and azithromycin as a treatment of COVID-19:
results of an open-label non-randomized clinical trial

https://www.sciencedirect.com/science/article/pii/S0924857920300996?via%3Dihub


Conclusion
Despite its small sample size our survey shows that hydroxychloroquine
treatment is significantly associated with viral load
reduction/disappearance in COVID-19 patients and its effect is
reinforced by azithromycin.

Yet even today I read a "news" article that declared that there was no evidence of the effectiveness of hydroxychloroquine.
 

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