G
Guy Macon
Guest
Rich Grise <null@example.net> says...
you are making between "instrument" and "cause." What I am saying
is that a prion is inserted into an organism and later there are a
lot more prions in that organism. You can call that whatever you
choose to call it.
Prions, like all other proteins, do survive UV, bleach, etc.
They are also not attacked by the immune system, which is really
good at fighting bacteria and virii but doesn't have any defense
at all against prions.
This raises the obvious question of why there are so few prion
diseases - why don't they just tear through the population? The
answer is that DNA and RNA based life is really, *really* good at
surviving and reproducing and (key concept) eating any proteins it
happens to stumble across - including prions. So prions are really
good at surviving our attempts at disinfecting them but are not
very good at reproducing. We pretty much had to give the prions
a helping hand by taking diseased cow corpses, killing all the DNA
and RNA in them without destroying the proteins, then feeding the
result to cows.
--
Guy Macon, Electronics Engineer & Project Manager for hire.
Remember Doc Brown from the _Back to the Future_ movies? Do you
have an "impossible" engineering project that only someone like
Doc Brown can solve? My resume is at http://www.guymacon.com/
I have no opinion one way or the other about the distinctionOK, infectious. If any protein could survive all that crap, and
still be virulent enough to get past the bodie's vast immune system,
and be the instrument of infection, it still is not the Cause.
you are making between "instrument" and "cause." What I am saying
is that a prion is inserted into an organism and later there are a
lot more prions in that organism. You can call that whatever you
choose to call it.
Prions, like all other proteins, do survive UV, bleach, etc.
They are also not attacked by the immune system, which is really
good at fighting bacteria and virii but doesn't have any defense
at all against prions.
This raises the obvious question of why there are so few prion
diseases - why don't they just tear through the population? The
answer is that DNA and RNA based life is really, *really* good at
surviving and reproducing and (key concept) eating any proteins it
happens to stumble across - including prions. So prions are really
good at surviving our attempts at disinfecting them but are not
very good at reproducing. We pretty much had to give the prions
a helping hand by taking diseased cow corpses, killing all the DNA
and RNA in them without destroying the proteins, then feeding the
result to cows.
--
Guy Macon, Electronics Engineer & Project Manager for hire.
Remember Doc Brown from the _Back to the Future_ movies? Do you
have an "impossible" engineering project that only someone like
Doc Brown can solve? My resume is at http://www.guymacon.com/