Breaking: SCIENTISTS: THE CORONAVIRUS HAS ALREADY MUTATED IN

"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

Whew- super bad news! For one thing that means a vaccine may not help, especially in older/weaker immune systems. They will be overwhelmed with viral damage quickly.

This stuff with the endothelial cells lining the blood vessels getting infected is super-bad.

https://futurism.com/neoscope/coronavirus-already-mutated-30-strains

 

[Phil Hobbs]

On 2020-04-23 18:37, whit3rd wrote:

On Thursday, April 23, 2020 at 10:42:55 AM UTC-7, bloggs.fre...@gmail.com wrote:
"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

Whew- super bad news! For one thing that means a vaccine may not help

Not too bad; the knowledge of thirty strains that all seem viable is good news. That means
the vaccine designers have thirty examples of variations that their target
vaccine oughtt not depend on. Alternately, it could be fought with multiple
different vaccines; having a sample of each strain makes the testing
protocols for vaccines more reliable, as well.

We understood previous diseases more poorly, yet developed vaccines for them,
since the 1700s.

Which occasionally worked. The 18th C smallpox ingrafting thing was
done out of desperation--the Montagus found out about it from the Turks.

Taking pus from smallpox sores, carrying it in walnut shells under your
armpit, and then scratching it into the skin of presumably-vulnerable
people isn't the sort of thing you'd do as a normal precaution.

Most of the vaccines developed for the 1918 'flu were worthless.

Cheers

Phil Hobbs

--
Dr Philip C D Hobbs
Principal Consultant
ElectroOptical Innovations LLC / Hobbs ElectroOptics
Optics, Electro-optics, Photonics, Analog Electronics
Briarcliff Manor NY 10510

http://electrooptical.net
http://hobbs-eo.com

 

[whit3rd]

On Thursday, April 23, 2020 at 10:42:55 AM UTC-7, bloggs.fre...@gmail.com wrote:

"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

Whew- super bad news! For one thing that means a vaccine may not help

Not too bad; the knowledge of thirty strains that all seem viable is good news. That means
the vaccine designers have thirty examples of variations that their target
vaccine oughtt not depend on. Alternately, it could be fought with multiple
different vaccines; having a sample of each strain makes the testing
protocols for vaccines more reliable, as well.

We understood previous diseases more poorly, yet developed vaccines for them,
since the 1700s.

 

[John Larkin]

On Thu, 23 Apr 2020 18:43:39 -0400, Phil Hobbs
<pcdhSpamMeSenseless@electrooptical.net> wrote:

On 2020-04-23 18:37, whit3rd wrote:
On Thursday, April 23, 2020 at 10:42:55 AM UTC-7, bloggs.fre...@gmail.com wrote:
"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

Whew- super bad news! For one thing that means a vaccine may not help

Not too bad; the knowledge of thirty strains that all seem viable is good news. That means
the vaccine designers have thirty examples of variations that their target
vaccine oughtt not depend on. Alternately, it could be fought with multiple
different vaccines; having a sample of each strain makes the testing
protocols for vaccines more reliable, as well.

We understood previous diseases more poorly, yet developed vaccines for them,
since the 1700s.


Which occasionally worked. The 18th C smallpox ingrafting thing was
done out of desperation--the Montagus found out about it from the Turks.

Taking pus from smallpox sores, carrying it in walnut shells under your
armpit, and then scratching it into the skin of presumably-vulnerable
people isn't the sort of thing you'd do as a normal precaution.

Most of the vaccines developed for the 1918 'flu were worthless.

Cheers

Phil Hobbs

They even named the bacteria that was known to cause the flu.

--

John Larkin Highland Technology, Inc
picosecond timing precision measurement

jlarkin att highlandtechnology dott com
http://www.highlandtechnology.com

 

On Thursday, April 23, 2020 at 1:42:55 PM UTC-4, bloggs.fre...@gmail.com wrote:
> "One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

That sounds like good news -- they've already identified a mild strain.
If it's weak enough, that's almost a vaccine right there.

Cheers,
James Arthur

 

[John Larkin]

On Thu, 23 Apr 2020 16:56:34 -0700 (PDT), dagmargoodboat@yahoo.com
wrote:

On Thursday, April 23, 2020 at 1:42:55 PM UTC-4, bloggs.fre...@gmail.com wrote:
"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

That sounds like good news -- they've already identified a mild strain.
If it's weak enough, that's almost a vaccine right there.

Cheers,
James Arthur

News now is that smoking is protective against coronavirus.

--

John Larkin Highland Technology, Inc
picosecond timing precision measurement

jlarkin att highlandtechnology dott com
http://www.highlandtechnology.com

 

On Thursday, April 23, 2020 at 7:56:39 PM UTC-4, dagmarg...@yahoo.com wrote:

On Thursday, April 23, 2020 at 1:42:55 PM UTC-4, bloggs.fre...@gmail.com wrote:
"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

That sounds like good news -- they've already identified a mild strain.
If it's weak enough, that's almost a vaccine right there.

Cheers,
James Arthur

They have the live virus deactivation down pat these days.

 

On Thursday, April 23, 2020 at 6:43:46 PM UTC-4, Phil Hobbs wrote:

On 2020-04-23 18:37, whit3rd wrote:
On Thursday, April 23, 2020 at 10:42:55 AM UTC-7, bloggs.fre...@gmail.com wrote:
"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

Whew- super bad news! For one thing that means a vaccine may not help

Not too bad; the knowledge of thirty strains that all seem viable is good news. That means
the vaccine designers have thirty examples of variations that their target
vaccine oughtt not depend on. Alternately, it could be fought with multiple
different vaccines; having a sample of each strain makes the testing
protocols for vaccines more reliable, as well.

We understood previous diseases more poorly, yet developed vaccines for them,
since the 1700s.


Which occasionally worked. The 18th C smallpox ingrafting thing was
done out of desperation--the Montagus found out about it from the Turks.

Taking pus from smallpox sores, carrying it in walnut shells under your
armpit, and then scratching it into the skin of presumably-vulnerable
people isn't the sort of thing you'd do as a normal precaution.

Most of the vaccines developed for the 1918 'flu were worthless.

Cuz they thought it was a bacteria. I guarantee you that if Louis Pasteur was still alive at the time, they would have had an effective vaccine.

Cheers

Phil Hobbs

--
Dr Philip C D Hobbs
Principal Consultant
ElectroOptical Innovations LLC / Hobbs ElectroOptics
Optics, Electro-optics, Photonics, Analog Electronics
Briarcliff Manor NY 10510

http://electrooptical.net
http://hobbs-eo.com

 

[Ricky C]

On Thursday, April 23, 2020 at 6:38:06 PM UTC-4, whit3rd wrote:

On Thursday, April 23, 2020 at 10:42:55 AM UTC-7, bloggs.fre...@gmail.com wrote:
"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

Whew- super bad news! For one thing that means a vaccine may not help

Not too bad; the knowledge of thirty strains that all seem viable is good news. That means
the vaccine designers have thirty examples of variations that their target
vaccine oughtt not depend on. Alternately, it could be fought with multiple
different vaccines; having a sample of each strain makes the testing
protocols for vaccines more reliable, as well.

We understood previous diseases more poorly, yet developed vaccines for them,
since the 1700s.

Does this virus infect cows? If it does, we are in like Flynn!

--

Rick C.

- Get 1,000 miles of free Supercharging
- Tesla referral code - https://ts.la/richard11209

 

[Ricky C]

On Thursday, April 23, 2020 at 8:33:18 PM UTC-4, bloggs.fre...@gmail.com wrote:

On Thursday, April 23, 2020 at 7:56:39 PM UTC-4, dagmarg...@yahoo.com wrote:
On Thursday, April 23, 2020 at 1:42:55 PM UTC-4, bloggs.fre...@gmail.com wrote:
"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

That sounds like good news -- they've already identified a mild strain.
If it's weak enough, that's almost a vaccine right there.

Cheers,
James Arthur

They have the live virus deactivation down pat these days.

Do they throw it in handcuffs or do they use the zip ties?

--

Rick C.

+ Get 1,000 miles of free Supercharging
+ Tesla referral code - https://ts.la/richard11209

 

[Bill Sloman]

On Friday, April 24, 2020 at 8:43:46 AM UTC+10, Phil Hobbs wrote:

On 2020-04-23 18:37, whit3rd wrote:
On Thursday, April 23, 2020 at 10:42:55 AM UTC-7, bloggs.fre...@gmail.com wrote:
"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

Whew- super bad news! For one thing that means a vaccine may not help

Not too bad; the knowledge of thirty strains that all seem viable is good news. That means the vaccine designers have thirty examples of variations that their target vaccine ought not depend on. Alternately, it could be fought with multiple different vaccines; having a sample of each strain makes the testing protocols for vaccines more reliable, as well.

We understood previous diseases more poorly, yet developed vaccines for them, since the 1700s.

Which occasionally worked. The 18th C smallpox ingrafting thing was
done out of desperation--the Montagus found out about it from the Turks.

Taking pus from smallpox sores, carrying it in walnut shells under your
armpit, and then scratching it into the skin of presumably - vulnerable
people isn't the sort of thing you'd do as a normal precaution.

You've skipped Jenner's innovation, which is exactly what we did as a normal precaution until we finally got rid of small pox completely

Jenner's vaccination used infection with cowpox - a related virus - to generate antibodies that also attacked small-pox. It was the first attenuated virus innoculation scheme, not that Jenner knew about viruses.

He'd noticed that dairymaids didn't get small pox, but had got cow-pox from the cow that they'd milked , and took it from there. Brilliant empirical thinking.

> Most of the vaccines developed for the 1918 'flu were worthless.

Influenza mutates fast enough that today's flu vaccines change from one flu season to the next, and only provide partial protection.

Using the right antigen to generate the right kind of antibody might work better.

https://www.pnas.org/content/117/15/8218?etoc
--
Bill Sloman, Sydney

 

[Bill Sloman]

On Friday, April 24, 2020 at 10:21:42 AM UTC+10, John Larkin wrote:

On Thu, 23 Apr 2020 16:56:34 -0700 (PDT), dagmargoodboat@yahoo.com
wrote:

On Thursday, April 23, 2020 at 1:42:55 PM UTC-4, bloggs.fre...@gmail.com wrote:
"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

That sounds like good news -- they've already identified a mild strain.
If it's weak enough, that's almost a vaccine right there.

News now is that smoking is protective against coronavirus.

But if you get infected anyway, the damage smoking has done to your lungs makes you more likely to die of it.

Granting John Larkin's gullibility, this is probably propaganda being circulated by pro-tobacco fake news industry. They long since moved over to telling us that climate change wasn't real, but some of the veterans may be having a nostalgia trip.

--
Bill Sloman, Sydney

 

[Mikko OH2HVJ]

Ricky C <gnuarm.deletethisbit@gmail.com> writes:

On Thursday, April 23, 2020 at 8:33:18 PM UTC-4, bloggs.fre...@gmail.com wrote:
On Thursday, April 23, 2020 at 7:56:39 PM UTC-4, dagmarg...@yahoo.com wrote:
They have the live virus deactivation down pat these days.

Do they throw it in handcuffs or do they use the zip ties?

Handcuffs. Check out the structure of beta-propiolactone, which is one
chemical used for deactivation!

https://www.biorxiv.org/content/10.1101/2020.04.17.046375v1.full.pdf

--
mikko

 

[Ricky C]

On Friday, April 24, 2020 at 12:24:16 AM UTC-4, Mikko OH2HVJ wrote:

Ricky C <gnuarm.deletethisbit@gmail.com> writes:

On Thursday, April 23, 2020 at 8:33:18 PM UTC-4, bloggs.fre...@gmail.com wrote:
On Thursday, April 23, 2020 at 7:56:39 PM UTC-4, dagmarg...@yahoo.com wrote:
They have the live virus deactivation down pat these days.

Do they throw it in handcuffs or do they use the zip ties?

Handcuffs. Check out the structure of beta-propiolactone, which is one
chemical used for deactivation!

https://www.biorxiv.org/content/10.1101/2020.04.17.046375v1.full.pdf

I think I just got rickrolled.

Yeah, I don't recall seeing a square molecule before.

--

Rick C.

-+ Get 1,000 miles of free Supercharging
-+ Tesla referral code - https://ts.la/richard11209

 

[Ricky C]

On Friday, April 24, 2020 at 12:09:13 AM UTC-4, Bill Sloman wrote:

You've skipped Jenner's innovation, which is exactly what we did as a normal precaution until we finally got rid of small pox completely

Jenner's vaccination used infection with cowpox - a related virus - to generate antibodies that also attacked small-pox. It was the first attenuated virus innoculation scheme, not that Jenner knew about viruses.

He'd noticed that dairymaids didn't get small pox, but had got cow-pox from the cow that they'd milked , and took it from there. Brilliant empirical thinking.

You say "he'd noticed" but he was *told* by the dairymaids that once you had cowpox you couldn't get small pox. But he did make the excellent connection to intentionally infecting people with cowpox to prevent the often fatal small pox disease.

"The record shows that it was there that Jenner heard a dairymaid say, “I shall never have smallpox for I have had cowpox. I shall never have an ugly pockmarked face.” It fact, it was a common belief that dairymaids were in some way protected from smallpox."

This is a very interesting read. I didn't know that prior to this they inoculated people with smallpox to protect them from smallpox. Seems the natural death rate was 14% with the rest often having terrible scarring. From some reason those inoculated (which was called variolated) was only 2% and they seldom had the scarring. Was it something about the subcutaneous inoculation that made it a less severe case? Jenner himself had been variolated.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200696/

--

Rick C.

-- Get 1,000 miles of free Supercharging
-- Tesla referral code - https://ts.la/richard11209

 

[Dave Platt]

In article <b29b99a4-049a-4d54-a60e-e0bb2ca7b52a@googlegroups.com>,
Ricky C <gnuarm.deletethisbit@gmail.com> wrote:

This is a very interesting read. I didn't know that prior to this they inoculated people with smallpox
to protect them from smallpox. Seems the natural death rate was 14% with the rest often having terrible
scarring. From some reason those inoculated (which was called variolated) was only 2% and they seldom
had the scarring. Was it something about the subcutaneous inoculation that made it a less severe case?
Jenner himself had been variolated.

I can think of a couple of possibilities:

- Route of infection. Smallpox was usually an airborn infection, if I
recall properly... as with measles and COVID-19, simply being in
the same room with an infectious person could getcha. This
suggests that the commonest route of infection was into the
respiratory tract... possibly at multiple sites in the lungs
simultaneously. That could result in multiple points of
establishment and a very rapid spread of the virus throughout the
system.

For variolation, the virus would introduced subcutaneously at a
single location. Perhaps it would take longer to spread widely
into the system, and/or encounter a more robust portion of the
immune system or elicit a stronger/faster response there?

- Possible difference in the virus itself, between viruses shed
naturally from a contagious individual (often in the earlier stages
of the infection) and viruses sampled from a smallpox lesion in the
skin?

One classic way of weakening a virus (so it can be used for a
vaccine) is to pass it through multiple generations of cell
culture. Most commonly, non-human cells are chosen for this. The
resulting viruses are "attenuated" - less able to cause disease in
humans. If I recall correctly, the mechanism seems to be that the
viruses must mutate in order to reproduce efficiently in the non-
human host cells (changes to receptor-binding proteins?) and so the
attenuation process preferentially selects for virus strains that are
more poorly adapted to infect human cells.

Perhaps something roughly similar happens within the body of an
individual patient, with the virus preferentially mutating/adapting
to different cell characteristics?

I think the former is more likely than the latter, but both ideas may
very well be wrong.

 

On Thursday, April 23, 2020 at 6:43:46 PM UTC-4, Phil Hobbs wrote:

On 2020-04-23 18:37, whit3rd wrote:
On Thursday, April 23, 2020 at 10:42:55 AM UTC-7, bloggs.fre...@gmail.com wrote:
"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

Whew- super bad news! For one thing that means a vaccine may not help

Not too bad; the knowledge of thirty strains that all seem viable is good news. That means
the vaccine designers have thirty examples of variations that their target
vaccine oughtt not depend on. Alternately, it could be fought with multiple
different vaccines; having a sample of each strain makes the testing
protocols for vaccines more reliable, as well.

We understood previous diseases more poorly, yet developed vaccines for them,
since the 1700s.


Which occasionally worked. The 18th C smallpox ingrafting thing was
done out of desperation--the Montagus found out about it from the Turks.

Taking pus from smallpox sores, carrying it in walnut shells under your
armpit, and then scratching it into the skin of presumably-vulnerable
people isn't the sort of thing you'd do as a normal precaution.

Most of the vaccines developed for the 1918 'flu were worthless.

Cheers

Phil Hobbs

The Brits used small pox against the American revolutionaries in
the Revolutionary War. The British soldiers, coming from
densely-populated areas, were largely immune; the rural Americans
had often never been ten miles from the place of their birth, and
were susceptible. Epidemic laid the Continentals low.

Washington responded with a secret (and illegal) vaccination program,
variolation, which saved the day.

This is a fair account...
https://www.realclearscience.com/blog/2016/09/how_vaccination_helped_win_the_revolutionary_war.html

There's an old trope that Americans used the trick to wipe out
the Indians, but it's not true. The one recorded incident of
contaminated blanket-passing was in 1763, years before the
revolution. British troops, besieged at Fort Pitt, tossed small-pox
contaminated blankets over the fort's wall, hoping to decimate their
foe, but there's no evidence the attempt succeeded.

e.g.
https://www.history.com/news/colonists-native-americans-smallpox-blankets

Cheers,
James Arthur

 

[Jeff Layman]

On 24/04/20 05:14, Bill Sloman wrote:

On Friday, April 24, 2020 at 10:21:42 AM UTC+10, John Larkin wrote:
On Thu, 23 Apr 2020 16:56:34 -0700 (PDT), dagmargoodboat@yahoo.com
wrote:

On Thursday, April 23, 2020 at 1:42:55 PM UTC-4, bloggs.fre...@gmail.com wrote:
"One strain, for example, appeared to generate 270 times the viral load — meaning the infected person produces 270 times as much of the virus— than the least potent strain."

That sounds like good news -- they've already identified a mild strain.
If it's weak enough, that's almost a vaccine right there.

News now is that smoking is protective against coronavirus.

But if you get infected anyway, the damage smoking has done to your lungs makes you more likely to die of it.

Granting John Larkin's gullibility, this is probably propaganda being circulated by pro-tobacco fake news industry. They long since moved over to telling us that climate change wasn't real, but some of the veterans may be having a nostalgia trip.

I was surprised at this and more than a little sceptical, but there
seems to be some science behind it - at least concerning the role of
nicotinic acetylcholine receptors:
<https://www.qeios.com/read/article/581>

--

Jeff

 

[Cursitor Doom]

On Fri, 24 Apr 2020 18:17:14 -0700, dagmargoodboat wrote:

There's an old trope that Americans used the trick to wipe out the
Indians, but it's not true. The one recorded incident of contaminated
blanket-passing was in 1763, years before the revolution. British
troops, besieged at Fort Pitt, tossed small-pox contaminated blankets
over the fort's wall, hoping to decimate their foe, but there's no
evidence the attempt succeeded.

Far more effective was using trebuchets to launch recently deceased
plague victims over castle walls to infect those holding out against a
siege. Sounds like something out of Monty Python, but was actually used
most famously in France in the late 1340s to make a crude bio-weapon out
of the Black Death which was contemporaneously sweeping across Europe.

 

Cursitor Doom <cd@not4mail.com> wrote in
news:r80vnb$3hc$1@dont-email.me:

Far more effective was using trebuchets to launch recently
deceased plague victims over castle walls to infect those holding
out against a siege.

Lock up all of Trump's family and most of his cabinet down at Fl, and
then lob the TrumpCorpseŠ at them using a circus cannon.

I cannot wait until the day I can say... TrumpCorspeŠ YAY!