Generic Drugs, There's A Reason They're So Cheap

Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

 

On Wednesday, October 30, 2019 at 4:55:42 PM UTC-4, bitrex wrote:

On 10/30/19 4:37 PM, bloggs.fredbloggs.fred@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/


I've always thought the loratadine (Claritin) that you can now buy over
the counter from generic mfgrs isn't nearly as effective at relieving
allergy/hay fever symptoms the name brand.

Yep- those big box generics aren't worth saving a couple of bucks if they don't work.

 

On Wednesday, October 30, 2019 at 4:57:28 PM UTC-4, Rick C wrote:

On Wednesday, October 30, 2019 at 4:37:32 PM UTC-4, bloggs.fre...@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

What I take away from this is that the US is still in the same camp with 7% of forms inspected having "data manipulation", in other words falsified! While we are complaining about India and China, why are the US numbers so high? Is 50% violation rate acceptable in the US while 67% in China is not?

It's the nature of the violation that is so much more important. The U.S. has a 7% data manipulation rate. I attribute that to a low level manager who's having problems meeting production schedules, and his/her actions are done on the sly unknown to higher ups. Whereas in Asia it's an entire organizational effort. Then the fact of the inspections in Asia being conducted on a pre-announced schedule means the real story is so much worse. The U.S. can tighten up its problems with criminal penalties that really hurt these people But there is the problem of many manufacturers being the only producer of that particular drug, which means shutting down the operation entirely is not an option. Right now we have this nightmare as an example, although no data integrity issues of record:
https://abcnews.go.com/Health/shortage-critical-cancer-drug-forcing-children/story?id=66411784

--

Rick C.

- Get 1,000 miles of free Supercharging
- Tesla referral code - https://ts.la/richard11209

 

[bitrex]

On 10/30/19 4:48 PM, bloggs.fredbloggs.fred@gmail.com wrote:

On Wednesday, October 30, 2019 at 4:37:32 PM UTC-4, bloggs.fre...@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

https://www.wired.com/story/8-ways-overseas-drug-manufacturers-dupe-fda/

Since they put the pseudoepinephrine-based drugs behind the counter or
aren't available at all in some locations, studies have shown the
phenylephrine hydrochloride-based cold meds are no more effective than
placebo.

When I've tried that type of medication when I have a cold symptoms feel
like 10% better at best

 

[bitrex]

On 10/30/19 4:37 PM, bloggs.fredbloggs.fred@gmail.com wrote:

Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

I've always thought the loratadine (Claritin) that you can now buy over
the counter from generic mfgrs isn't nearly as effective at relieving
allergy/hay fever symptoms the name brand.

 

On Wednesday, October 30, 2019 at 4:37:32 PM UTC-4, bloggs.fre...@gmail.com wrote:

Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

https://www.wired.com/story/8-ways-overseas-drug-manufacturers-dupe-fda/

 

[Rick C]

On Wednesday, October 30, 2019 at 4:37:32 PM UTC-4, bloggs.fre...@gmail.com wrote:

Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

What I take away from this is that the US is still in the same camp with 7% of forms inspected having "data manipulation", in other words falsified! While we are complaining about India and China, why are the US numbers so high? Is 50% violation rate acceptable in the US while 67% in China is not?

--

Rick C.

- Get 1,000 miles of free Supercharging
- Tesla referral code - https://ts.la/richard11209

 

[John Larkin]

On Wed, 30 Oct 2019 16:55:36 -0400, bitrex <user@example.net> wrote:

On 10/30/19 4:37 PM, bloggs.fredbloggs.fred@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/


I've always thought the loratadine (Claritin) that you can now buy over
the counter from generic mfgrs isn't nearly as effective at relieving
allergy/hay fever symptoms the name brand.

Tried nasal steroids? Flonase is OTC now.



--

John Larkin Highland Technology, Inc
picosecond timing precision measurement

jlarkin att highlandtechnology dott com
http://www.highlandtechnology.com

 

[Rick C]

On Wednesday, October 30, 2019 at 5:19:19 PM UTC-4, bloggs.fre...@gmail.com wrote:

On Wednesday, October 30, 2019 at 4:57:28 PM UTC-4, Rick C wrote:
On Wednesday, October 30, 2019 at 4:37:32 PM UTC-4, bloggs.fre...@gmail..com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

What I take away from this is that the US is still in the same camp with 7% of forms inspected having "data manipulation", in other words falsified! While we are complaining about India and China, why are the US numbers so high? Is 50% violation rate acceptable in the US while 67% in China is not?

It's the nature of the violation that is so much more important. The U.S. has a 7% data manipulation rate. I attribute that to a low level manager who's having problems meeting production schedules, and his/her actions are done on the sly unknown to higher ups. Whereas in Asia it's an entire organizational effort. Then the fact of the inspections in Asia being conducted on a pre-announced schedule means the real story is so much worse. The U.S. can tighten up its problems with criminal penalties that really hurt these people But there is the problem of many manufacturers being the only producer of that particular drug, which means shutting down the operation entirely is not an option. Right now we have this nightmare as an example, although no data integrity issues of record:
https://abcnews.go.com/Health/shortage-critical-cancer-drug-forcing-children/story?id=66411784

So you make up some justification for the problem in the US only paying attention to a single figure while ignoring the number that is scary, 49% of the inspections in the US show problems!!! HALF!!! WTF!!!

If I got a ticket half the time I drove by a cop I would not have a license anymore.

I've read that there are 200,000 deaths each year in the US due to prescription drug mistakes. Now we find a terrible safety record in the factories making the drugs.

--

Rick C.

-- Get 1,000 miles of free Supercharging
-- Tesla referral code - https://ts.la/richard11209

 

[Rick C]

On Wednesday, October 30, 2019 at 5:00:17 PM UTC-4, bitrex wrote:

On 10/30/19 4:48 PM, bloggs.fredbloggs.fred@gmail.com wrote:
On Wednesday, October 30, 2019 at 4:37:32 PM UTC-4, bloggs.fre...@gmail..com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

https://www.wired.com/story/8-ways-overseas-drug-manufacturers-dupe-fda/


Since they put the pseudoepinephrine-based drugs behind the counter or
aren't available at all in some locations, studies have shown the
phenylephrine hydrochloride-based cold meds are no more effective than
placebo.

When I've tried that type of medication when I have a cold symptoms feel
like 10% better at best

That's like the recent semi-insane restrictions on opioids. I get that these drugs are used for improper purposes, but does that justify making them unavailable for those who need to use them responsibly?

Why is it that we can't find ways to limit the misuse of drugs that doesn't harm others by making them unavailable?

--

Rick C.

+ Get 1,000 miles of free Supercharging
+ Tesla referral code - https://ts.la/richard11209

 

On Wednesday, October 30, 2019 at 6:14:10 PM UTC-4, Rick C wrote:

On Wednesday, October 30, 2019 at 5:19:19 PM UTC-4, bloggs.fre...@gmail.com wrote:
On Wednesday, October 30, 2019 at 4:57:28 PM UTC-4, Rick C wrote:
On Wednesday, October 30, 2019 at 4:37:32 PM UTC-4, bloggs.fre...@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

What I take away from this is that the US is still in the same camp with 7% of forms inspected having "data manipulation", in other words falsified! While we are complaining about India and China, why are the US numbers so high? Is 50% violation rate acceptable in the US while 67% in China is not?

It's the nature of the violation that is so much more important. The U.S. has a 7% data manipulation rate. I attribute that to a low level manager who's having problems meeting production schedules, and his/her actions are done on the sly unknown to higher ups. Whereas in Asia it's an entire organizational effort. Then the fact of the inspections in Asia being conducted on a pre-announced schedule means the real story is so much worse. The U.S. can tighten up its problems with criminal penalties that really hurt these people But there is the problem of many manufacturers being the only producer of that particular drug, which means shutting down the operation entirely is not an option. Right now we have this nightmare as an example, although no data integrity issues of record:
https://abcnews.go.com/Health/shortage-critical-cancer-drug-forcing-children/story?id=66411784

So you make up some justification for the problem in the US only paying attention to a single figure while ignoring the number that is scary, 49% of the inspections in the US show problems!!! HALF!!! WTF!!!

If I got a ticket half the time I drove by a cop I would not have a license anymore.

I've read that there are 200,000 deaths each year in the US due to prescription drug mistakes. Now we find a terrible safety record in the factories making the drugs.

You don't know the nature of those violations, inspections can be very nitpicky. Spot analysis of product from U.S. operations has never revealed the kind of widespread crazy results they get for the Asian product, stuff like doses with no active ingredient at all.

--

Rick C.

-- Get 1,000 miles of free Supercharging
-- Tesla referral code - https://ts.la/richard11209

 

[Rick C]

On Wednesday, October 30, 2019 at 6:41:44 PM UTC-4, bloggs.fre...@gmail.com wrote:

On Wednesday, October 30, 2019 at 6:14:10 PM UTC-4, Rick C wrote:
On Wednesday, October 30, 2019 at 5:19:19 PM UTC-4, bloggs.fre...@gmail..com wrote:
On Wednesday, October 30, 2019 at 4:57:28 PM UTC-4, Rick C wrote:
On Wednesday, October 30, 2019 at 4:37:32 PM UTC-4, bloggs.fre...@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

What I take away from this is that the US is still in the same camp with 7% of forms inspected having "data manipulation", in other words falsified! While we are complaining about India and China, why are the US numbers so high? Is 50% violation rate acceptable in the US while 67% in China is not?

It's the nature of the violation that is so much more important. The U.S. has a 7% data manipulation rate. I attribute that to a low level manager who's having problems meeting production schedules, and his/her actions are done on the sly unknown to higher ups. Whereas in Asia it's an entire organizational effort. Then the fact of the inspections in Asia being conducted on a pre-announced schedule means the real story is so much worse. The U.S. can tighten up its problems with criminal penalties that really hurt these people But there is the problem of many manufacturers being the only producer of that particular drug, which means shutting down the operation entirely is not an option. Right now we have this nightmare as an example, although no data integrity issues of record:
https://abcnews.go.com/Health/shortage-critical-cancer-drug-forcing-children/story?id=66411784

So you make up some justification for the problem in the US only paying attention to a single figure while ignoring the number that is scary, 49% of the inspections in the US show problems!!! HALF!!! WTF!!!

If I got a ticket half the time I drove by a cop I would not have a license anymore.

I've read that there are 200,000 deaths each year in the US due to prescription drug mistakes. Now we find a terrible safety record in the factories making the drugs.

You don't know the nature of those violations, inspections can be very nitpicky. Spot analysis of product from U.S. operations has never revealed the kind of widespread crazy results they get for the Asian product, stuff like doses with no active ingredient at all.

Your report doesn't indicate any of that. Where did you read this additional data?

My point is regardless of what the problems are in China and elsewhere, 50% is a failing grade here in the US. It isn't justified by pointing to other countries and saying we are so much better than them!

--

Rick C.

-+ Get 1,000 miles of free Supercharging
-+ Tesla referral code - https://ts.la/richard11209

 

[John Robertson]

On 2019/10/30 5:16 p.m., Rick C wrote:

On Wednesday, October 30, 2019 at 6:41:44 PM UTC-4, bloggs.fre...@gmail.com wrote:
On Wednesday, October 30, 2019 at 6:14:10 PM UTC-4, Rick C wrote:
On Wednesday, October 30, 2019 at 5:19:19 PM UTC-4, bloggs.fre...@gmail.com wrote:
On Wednesday, October 30, 2019 at 4:57:28 PM UTC-4, Rick C wrote:
On Wednesday, October 30, 2019 at 4:37:32 PM UTC-4, bloggs.fre...@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

What I take away from this is that the US is still in the same camp with 7% of forms inspected having "data manipulation", in other words falsified! While we are complaining about India and China, why are the US numbers so high? Is 50% violation rate acceptable in the US while 67% in China is not?

It's the nature of the violation that is so much more important. The U.S. has a 7% data manipulation rate. I attribute that to a low level manager who's having problems meeting production schedules, and his/her actions are done on the sly unknown to higher ups. Whereas in Asia it's an entire organizational effort. Then the fact of the inspections in Asia being conducted on a pre-announced schedule means the real story is so much worse. The U.S. can tighten up its problems with criminal penalties that really hurt these people But there is the problem of many manufacturers being the only producer of that particular drug, which means shutting down the operation entirely is not an option. Right now we have this nightmare as an example, although no data integrity issues of record:
https://abcnews.go.com/Health/shortage-critical-cancer-drug-forcing-children/story?id=66411784

So you make up some justification for the problem in the US only paying attention to a single figure while ignoring the number that is scary, 49% of the inspections in the US show problems!!! HALF!!! WTF!!!

If I got a ticket half the time I drove by a cop I would not have a license anymore.

I've read that there are 200,000 deaths each year in the US due to prescription drug mistakes. Now we find a terrible safety record in the factories making the drugs.

You don't know the nature of those violations, inspections can be very nitpicky. Spot analysis of product from U.S. operations has never revealed the kind of widespread crazy results they get for the Asian product, stuff like doses with no active ingredient at all.

Your report doesn't indicate any of that. Where did you read this additional data?

My point is regardless of what the problems are in China and elsewhere, 50% is a failing grade here in the US. It isn't justified by pointing to other countries and saying we are so much better than them!

The joys of deregulation - more people die...

John :-#(#

 

[bitrex]

On 10/30/19 6:31 PM, John Larkin wrote:

On Wed, 30 Oct 2019 16:55:36 -0400, bitrex <user@example.net> wrote:

On 10/30/19 4:37 PM, bloggs.fredbloggs.fred@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/


I've always thought the loratadine (Claritin) that you can now buy over
the counter from generic mfgrs isn't nearly as effective at relieving
allergy/hay fever symptoms the name brand.

Tried nasal steroids? Flonase is OTC now.

Yeah that's next step. Spring allergies have gotten worse as I've gotten
older also the pollen season in NE is much longer and heavier than it
once was due to the climate change that isn't happening.

Whether name brand or generic Claritin it starts to lose effectiveness
sooner or later if you take it every day, so probably need to "rotate
the shields" and switch approaches after a while at least.

 

[bitrex]

On 10/30/19 5:20 PM, bloggs.fredbloggs.fred@gmail.com wrote:

On Wednesday, October 30, 2019 at 4:55:42 PM UTC-4, bitrex wrote:
On 10/30/19 4:37 PM, bloggs.fredbloggs.fred@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/


I've always thought the loratadine (Claritin) that you can now buy over
the counter from generic mfgrs isn't nearly as effective at relieving
allergy/hay fever symptoms the name brand.

Yep- those big box generics aren't worth saving a couple of bucks if they don't work.

Another drug I've definitely noticed a quality difference is the
sleeping med Ambien I've had to use occasionally due to e.g. needing to
get some sleep while recovering at home after a surgery.

For me the 10 mg of the name brand standard release was rapid lights-out
time. The 10 mg of the generic was hmm...maybe feel a little tired? not
much happening...took about an hour to fall asleep with the
made-in-India generic. Probably just fell asleep naturally, placebo

 

On Wednesday, October 30, 2019 at 8:16:52 PM UTC-4, Rick C wrote:

On Wednesday, October 30, 2019 at 6:41:44 PM UTC-4, bloggs.fre...@gmail.com wrote:
On Wednesday, October 30, 2019 at 6:14:10 PM UTC-4, Rick C wrote:
On Wednesday, October 30, 2019 at 5:19:19 PM UTC-4, bloggs.fre...@gmail.com wrote:
On Wednesday, October 30, 2019 at 4:57:28 PM UTC-4, Rick C wrote:
On Wednesday, October 30, 2019 at 4:37:32 PM UTC-4, bloggs.fre...@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

What I take away from this is that the US is still in the same camp with 7% of forms inspected having "data manipulation", in other words falsified! While we are complaining about India and China, why are the US numbers so high? Is 50% violation rate acceptable in the US while 67% in China is not?

It's the nature of the violation that is so much more important. The U.S. has a 7% data manipulation rate. I attribute that to a low level manager who's having problems meeting production schedules, and his/her actions are done on the sly unknown to higher ups. Whereas in Asia it's an entire organizational effort. Then the fact of the inspections in Asia being conducted on a pre-announced schedule means the real story is so much worse. The U.S. can tighten up its problems with criminal penalties that really hurt these people But there is the problem of many manufacturers being the only producer of that particular drug, which means shutting down the operation entirely is not an option. Right now we have this nightmare as an example, although no data integrity issues of record:
https://abcnews.go.com/Health/shortage-critical-cancer-drug-forcing-children/story?id=66411784

So you make up some justification for the problem in the US only paying attention to a single figure while ignoring the number that is scary, 49% of the inspections in the US show problems!!! HALF!!! WTF!!!

If I got a ticket half the time I drove by a cop I would not have a license anymore.

I've read that there are 200,000 deaths each year in the US due to prescription drug mistakes. Now we find a terrible safety record in the factories making the drugs.

You don't know the nature of those violations, inspections can be very nitpicky. Spot analysis of product from U.S. operations has never revealed the kind of widespread crazy results they get for the Asian product, stuff like doses with no active ingredient at all.

Your report doesn't indicate any of that. Where did you read this additional data?

Do you have any idea of the concept of accumulated background knowledge from previous readings? Or is it all you know how to do is "gleam" information from what's set in front of you and take that as the totality of what there is to know about the subject?

My point is regardless of what the problems are in China and elsewhere, 50% is a failing grade here in the US. It isn't justified by pointing to other countries and saying we are so much better than them!

--

Rick C.

-+ Get 1,000 miles of free Supercharging
-+ Tesla referral code - https://ts.la/richard11209

 

[Rick C]

On Thursday, October 31, 2019 at 12:28:22 PM UTC-4, bloggs.fre...@gmail.com wrote:

On Wednesday, October 30, 2019 at 8:16:52 PM UTC-4, Rick C wrote:
On Wednesday, October 30, 2019 at 6:41:44 PM UTC-4, bloggs.fre...@gmail..com wrote:
On Wednesday, October 30, 2019 at 6:14:10 PM UTC-4, Rick C wrote:
On Wednesday, October 30, 2019 at 5:19:19 PM UTC-4, bloggs.fre...@gmail.com wrote:
On Wednesday, October 30, 2019 at 4:57:28 PM UTC-4, Rick C wrote:
On Wednesday, October 30, 2019 at 4:37:32 PM UTC-4, bloggs.fre....@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/

What I take away from this is that the US is still in the same camp with 7% of forms inspected having "data manipulation", in other words falsified! While we are complaining about India and China, why are the US numbers so high? Is 50% violation rate acceptable in the US while 67% in China is not?

It's the nature of the violation that is so much more important. The U.S. has a 7% data manipulation rate. I attribute that to a low level manager who's having problems meeting production schedules, and his/her actions are done on the sly unknown to higher ups. Whereas in Asia it's an entire organizational effort. Then the fact of the inspections in Asia being conducted on a pre-announced schedule means the real story is so much worse. The U.S. can tighten up its problems with criminal penalties that really hurt these people But there is the problem of many manufacturers being the only producer of that particular drug, which means shutting down the operation entirely is not an option. Right now we have this nightmare as an example, although no data integrity issues of record:
https://abcnews.go.com/Health/shortage-critical-cancer-drug-forcing-children/story?id=66411784

So you make up some justification for the problem in the US only paying attention to a single figure while ignoring the number that is scary, 49% of the inspections in the US show problems!!! HALF!!! WTF!!!

If I got a ticket half the time I drove by a cop I would not have a license anymore.

I've read that there are 200,000 deaths each year in the US due to prescription drug mistakes. Now we find a terrible safety record in the factories making the drugs.

You don't know the nature of those violations, inspections can be very nitpicky. Spot analysis of product from U.S. operations has never revealed the kind of widespread crazy results they get for the Asian product, stuff like doses with no active ingredient at all.

Your report doesn't indicate any of that. Where did you read this additional data?

Do you have any idea of the concept of accumulated background knowledge from previous readings? Or is it all you know how to do is "gleam" information from what's set in front of you and take that as the totality of what there is to know about the subject?

I asked you where you got your information and this is your reply. I expected there would be no credible source.

--

Rick C.

+- Get 1,000 miles of free Supercharging
+- Tesla referral code - https://ts.la/richard11209

 

[John Larkin]

On Thu, 31 Oct 2019 12:20:39 -0400, bitrex <user@example.net> wrote:

On 10/30/19 6:31 PM, John Larkin wrote:
On Wed, 30 Oct 2019 16:55:36 -0400, bitrex <user@example.net> wrote:

On 10/30/19 4:37 PM, bloggs.fredbloggs.fred@gmail.com wrote:
Drugs are nothing if not properly manufactured, and that includes lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart transplant patients whose anti-rejection medication was working fine ended up suffering organ rejection after taking an ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-problematic-china-india-generic-drug-plants/


I've always thought the loratadine (Claritin) that you can now buy over
the counter from generic mfgrs isn't nearly as effective at relieving
allergy/hay fever symptoms the name brand.

Tried nasal steroids? Flonase is OTC now.




Yeah that's next step. Spring allergies have gotten worse as I've gotten
older also the pollen season in NE is much longer and heavier than it
once was due to the climate change that isn't happening.

I had some job interviews back east, but New Jersey is the ragweed
capital of the world, and it would have been horrible.

A lot of allergens are man-made, not so much climate change as the way
we manage the land.

Whether name brand or generic Claritin it starts to lose effectiveness
sooner or later if you take it every day, so probably need to "rotate
the shields" and switch approaches after a while at least.

Try Flonase. It takes a few days to kick in, but it really works.

--

John Larkin Highland Technology, Inc
picosecond timing precision measurement

jlarkin att highlandtechnology dott com
http://www.highlandtechnology.com

 

[John Doe]

I'm sure it's already been said in this thread...
The main reason generic drugs are relatively cheap is because the
original maker is attempting to recover the cost of research.

And Yes, of course you can get crap products of all sorts from India
and China.

That's what brand names are for. That's why China isn't interested
in branding. They make crap products and think offering the lowest
price is all that matters. Some fools fall for it.

China is perfecting the art of making things that are
barely/marginally worth something.





bloggs.fredbloggs.fred@gmail.com wrote:

Drugs are nothing if not properly manufactured, and that includes
lots and lots of in-process testing.

At the Cleveland Clinic, as “Bottle of Lies” chronicles, heart
transplant patients whose anti-rejection medication was working
fine ended up suffering organ rejection after taking an
ineffective Indian-made immunosuppressant.

https://www.statnews.com/2019/10/29/data-falsification-still-proble
matic-china-india-generic-drug-plants/